Mopreme Shakur, Tupac’s brother tells TMZ Hip Hop that his issue with Drake using an AI Tupac voice is that he weaponized it … all for a rap battle.

Mopreme tells us Drake using Pac’s voice is like bringing out a tank, or even going with a nuclear option — and he thinks the battle should be 1-on-1 … with no outside help.

Of course, Mopreme isn’t naive to the fact Kendrick is a West Coast legend himself inspired by Pac … and Drake is trying to push some buttons.

Jay-Z famously said he’d kill “ants with a sledgehammer” in his “Takeover” diss against Nas, and Tupac himself outlined the “Secretz of War” with a totalitarian attitude — so, Drake might be following their lead by using Pac’s voice.

Fans defending Drake pointed out Kendrick famously used a Tupac interview to close out “To Pimp a Butterfly” — the album J. Cole failed to slam — but Mopreme agrees with that move because it was an homage.

He has nothing but love for Kendrick, Drake and Cole … and says they all need to make sure the rap battle remains sport, and doesn’t escalate into physical violence.

Mopreme says of course he loves hearing his brother’s voice … just not in a battle.

For his part, Snoop was left speechless when fans cornered him for a reaction.

Mopreme admits Drake’s song made him realize AI “is a hell of a tool” … and in Pac’s case, he’s worried younger generations might confuse the artificial Pac with the real deal.

Suge Knight‘s reaction was similar to Mopreme’s … he says Pac was king and should never be stooped down to do a pawn’s bidding.